Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385658 | 0.84 | ACHE (0.42) | ACHELMNA | |
| SCHEMBL9380948 | 0.78 | ACHE (0.39) | ACHEHPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL9381879 | 0.72 | GALR2 (0.34) | ACHE | |
| SCHEMBL9381904 | 0.65 | ACHE (0.51) | ACHEHPGDHTTSMN1; SMN2 | |
| SCHEMBL9382126 | 0.65 | ACHE (0.34) | ACHE | |
| SCHEMBL8970334 | 0.65 | NOS3 (0.42) | ACHEHPGDHTT | |
| SCHEMBL9379110 | 0.65 | ACHE (0.39) | ACHEHPGDSMN1; SMN2 | |
| SCHEMBL9381689 | 0.65 | ACHE (0.48) | ACHELMNA | |
| SCHEMBL25835641 | 0.64 | KLK7 (0.49) | ACHELMNA | |
| SCHEMBL6921297 | 0.63 | ACHE (0.70) | ACHELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597956-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1994-05-25 | — | — | EP | disclosed |