Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380409 | 0.80 | MEN1 (0.37) | MEN1KMT2ANPC1HTR2CCYP19A1 | |
| SCHEMBL9378128 | 0.80 | MEN1 (0.37) | MEN1KMT2ANPC1HTR2CCYP19A1 | |
| SCHEMBL10372159 | 0.76 | LMNA (0.39) | MEN1KMT2ACYP2C19ALDH1A1NFKB1 | |
| SCHEMBL9377930 | 0.76 | LMNA (0.39) | MEN1KMT2ACYP2C19ALDH1A1NFKB1 | |
| SCHEMBL9382305 | 0.73 | HTR2C (0.40) | CYP2C19CHRM2HTR2CLMNAHTR2A | |
| SCHEMBL11162641 | 0.72 | HTR2C (0.50) | MEN1KMT2AKDM4ENPC1CYP3A4 | |
| SCHEMBL3762403 | 0.68 | HTR2C (0.46) | MEN1KMT2AKDM4ENPC1CYP3A4 | |
| SCHEMBL23676966 | 0.67 | HTR2C (0.61) | MEN1KMT2AKDM4ENPC1CYP3A4 | |
| SCHEMBL9692360 | 0.67 | TSHR (0.51) | MEN1KMT2AKDM4ENPC1CYP3A4 | |
| SCHEMBL25259513 | 0.66 | RELA (0.62) | RELACHRM2CHRM1CHRM3CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335315-B1 | New alkanephenones | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5149717-A | Alkanophenones useful for treating allergies | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0335315-A1 | New alkanephenones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |