Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378128 | 1.00 | MEN1 (0.37) | MEN1KMT2AHTR2CPBRM1CYP19A1 | |
| SCHEMBL9802086 | 0.83 | KMT2A (0.41) | MEN1KMT2AHTR2CPBRM1CYP19A1 | |
| SCHEMBL9378737 | 0.83 | KMT2A (0.41) | MEN1KMT2AHTR2CPBRM1CYP19A1 | |
| SCHEMBL9380385 | 0.80 | MEN1 (0.41) | MEN1KMT2AHTR2CCYP19A1HTR2A | |
| SCHEMBL9377930 | 0.79 | LMNA (0.39) | MEN1KMT2A | |
| SCHEMBL10372159 | 0.79 | LMNA (0.39) | MEN1KMT2A | |
| SCHEMBL9382305 | 0.77 | HTR2C (0.40) | HTR2CPBRM1HTR2AHTR2B | |
| SCHEMBL9377796 | 0.76 | ERN1 (0.40) | NPC1 | |
| SCHEMBL5852622 | 0.69 | ACHE (0.48) | MEN1KMT2AHTR2CCYP19A1ACHE | |
| SCHEMBL30717247 | 0.69 | ACHE (0.48) | MEN1KMT2AHTR2CCYP19A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335315-B1 | New alkanephenones | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5149717-A | Alkanophenones useful for treating allergies | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0335315-A1 | New alkanephenones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |