Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032805 | 0.93 | RAB9A (0.43) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9032937 | 0.92 | NPC1 (0.43) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9032895 | 0.85 | RAB9A (0.43) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9033686 | 0.78 | HPGD (0.43) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9209788 | 0.76 | NPC1 (0.47) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9032267 | 0.76 | MAOB (0.41) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9380510 | 0.75 | LMNA (0.44) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9033191 | 0.75 | LMNA (0.44) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 | |
| SCHEMBL9032302 | 0.73 | MAOB (0.43) | SMN1; SMN2RAB9ANPC1MAPTKMT2A | |
| SCHEMBL9031467 | 0.73 | MAOA (0.43) | SMN1; SMN2RAB9ALMNANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621864-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES. | CIBA GEIGY AG (CH) | 1994-11-02 | — | — | EP | claimed |
| EP-0621864-A1 | 2-(2-BENZO(b)THIENYL)-3-METHOXYACRYLATE AND -2-IMINOACETATE DERIVATIVES TO BE USED AS PESTICIDES. | CIBA GEIGY AG (CH) | 1994-11-02 | — | — | EP | disclosed |