Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9378737 | 1.00 | KMT2A (0.41) | KMT2AMEN1HTR2CACHECYP19A1 | |
| SCHEMBL9380409 | 0.83 | MEN1 (0.37) | KMT2AMEN1HTR2CACHECYP19A1 | |
| SCHEMBL9378128 | 0.83 | MEN1 (0.37) | KMT2AMEN1HTR2CACHECYP19A1 | |
| SCHEMBL9802330 | 0.79 | MEN1 (0.38) | KMT2AMEN1ACHECYP19A1HDAC4 | |
| SCHEMBL30967867 | 0.78 | FAAH (0.31) | — | |
| SCHEMBL10034792 | 0.76 | EPHX1 (0.41) | KMT2AMEN1HTR2BLMNAMAPT | |
| SCHEMBL6109677 | 0.76 | EPHX1 (0.41) | KMT2AMEN1HTR2BLMNAMAPT | |
| SCHEMBL5301553 | 0.76 | EPHX1 (0.41) | KMT2AMEN1HTR2BLMNAMAPT | |
| SCHEMBL10400049 | 0.76 | EPHX1 (0.41) | KMT2AMEN1HTR2BLMNAMAPT | |
| SCHEMBL5852622 | 0.74 | ACHE (0.48) | KMT2AMEN1HTR2CACHECYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228045-B1 | AROMATIC THIOETHERS | CIBA-GEIGY AG (CH) | 1991-04-03 | — | — | EP | disclosed |
| US-4785004-A | ANTIALLERGENS, ANTIHISTAMINES | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| EP-0228045-A2 | Aromatic thioethers | CIBA-GEIGY AG (CH) | 1987-07-08 | — | — | EP | disclosed |