Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 8/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380409 | 0.81 | MEN1 (0.37) | SLC6A3HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL9378128 | 0.81 | MEN1 (0.37) | SLC6A3HTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL10372159 | 0.79 | LMNA (0.39) | MAPTGAAALDH1A1TSHRMEN1 | |
| SCHEMBL9377930 | 0.79 | LMNA (0.39) | MAPTGAAALDH1A1TSHRMEN1 | |
| SCHEMBL10374320 | 0.77 | DRD2 (0.38) | TSHR | |
| SCHEMBL9380385 | 0.77 | MEN1 (0.41) | GAAALDH1A1HPGDHTR2AHTR2C | |
| SCHEMBL9378389 | 0.77 | HTR2C (0.40) | TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL9382305 | 0.77 | HTR2C (0.40) | TSHRHTR2AHTR2CHTR2B | |
| SCHEMBL9377796 | 0.73 | ERN1 (0.40) | GAAALDH1A1TSHR | |
| SCHEMBL9384954 | 0.73 | ERN1 (0.40) | GAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335315-B1 | New alkanephenones | CIBA GEIGY AG (CH) | 1994-06-22 | — | — | EP | disclosed |
| US-5149717-A | Alkanophenones useful for treating allergies | CIBA-GEIGY CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| EP-0335315-A1 | New alkanephenones | CIBA-GEIGY AG (CH) | 1989-10-04 | — | — | EP | disclosed |