Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CTSG | P08311 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9382048 | 0.87 | CA12 (0.35) | FKBP1ARAB9ACA12CA1CA2 | |
| SCHEMBL30278681 | 0.85 | CYP19A1 (0.44) | FKBP1ACA12CA1CA2CA9 | |
| SCHEMBL20101959 | 0.82 | SIGMAR1 (0.33) | RAB9ACA12CA1CA2CA9 | |
| SCHEMBL5702051 | 0.80 | RAB9A (0.48) | RAB9ACHRM1CYP19A1SIGMAR1ELANE | |
| SCHEMBL7877679 | 0.80 | RAB9A (0.48) | RAB9ACHRM1CYP19A1SIGMAR1ELANE | |
| SCHEMBL5702004 | 0.80 | RAB9A (0.48) | RAB9ACHRM1CYP19A1SIGMAR1ELANE | |
| SCHEMBL27305125 | 0.80 | PDK1 (0.47) | RAB9ACA12CA1CA2CA9 | |
| SCHEMBL28629931 | 0.80 | PDK1 (0.47) | RAB9ACA12CA1CA2CA9 | |
| SCHEMBL9192532 | 0.80 | PDK1 (0.47) | RAB9ACA12CA1CA2CA9 | |
| SCHEMBL20101960 | 0.79 | CYP19A1 (0.36) | CHRM1CYP19A1SIGMAR1ERN1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394991-B1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5102877-A | Carbapenicillin antibiotics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0394991-A1 | 1-Azabicyclo(3.2.0)Hept-2-Ene-2-carboxylic acid compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |