Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 3/20 | 0.48 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.47 |
| ▸ | BCL2 | P10415 | 3/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.47 |
| ▸ | BAD | Q92934 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389291 | 0.87 | ALOX15 (0.51) | ALOX15KDM4EALDH1A1HPGDTDP1 | |
| SCHEMBL20515870 | 0.85 | ALOX15 (0.69) | ALOX15KDM4EALDH1A1HPGDNCF1 | |
| SCHEMBL30438659 | 0.85 | ALOX15 (0.69) | ALOX15KDM4EALDH1A1HPGDNCF1 | |
| SCHEMBL30438115 | 0.85 | ALOX15 (0.64) | ALOX15ALDH1A1HPGDNCF1 | |
| SCHEMBL9384536 | 0.83 | ALOX15 (0.62) | ALOX15ALDH1A1HPGDNCF1 | |
| SCHEMBL31389276 | 0.83 | ALOX15 (0.58) | ALOX15ALDH1A1TDP1MCL1MRGPRX4 | |
| SCHEMBL31389295 | 0.82 | ALOX15 (0.61) | ALOX15ALDH1A1HPGDNCF1 | |
| SCHEMBL9385188 | 0.82 | ALOX15 (0.61) | ALOX15NCF1 | |
| SCHEMBL18528819 | 0.80 | ALOX15 (0.70) | ALOX15KDM4EALDH1A1HPGDNCF1 | |
| SCHEMBL9378807 | 0.80 | ALOX15 (0.66) | ALOX15KDM4EALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |