Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154834 | 0.87 | MEN1 (0.31) | — | |
| SCHEMBL9159401 | 0.79 | SMN1; SMN2 (0.38) | NPC1RAB9A | |
| SCHEMBL9157591 | 0.71 | SLC5A2 (0.32) | — | |
| SCHEMBL9046241 | 0.71 | SLC6A3 (0.47) | FLT3TYRO3MERTKGAS6 | |
| SCHEMBL15349230 | 0.71 | SLC6A3 (0.39) | NPC1RAB9A | |
| SCHEMBL2043681 | 0.70 | KIF11 (0.31) | — | |
| SCHEMBL28003150 | 0.69 | SLC6A3 (0.35) | — | |
| SCHEMBL9264679 | 0.68 | SLC6A3 (0.41) | FLT3TYRO3MERTKGAS6NPC1 | |
| SCHEMBL9159853 | 0.68 | — | — | |
| SCHEMBL15356486 | 0.67 | DRD2 (0.42) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579304-A1 | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis | MERCK FROSST CANADA INC. (CA) | 1994-01-19 | — | — | EP | disclosed |