Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385161 | 1.00 | GLO1 (0.58) | GLO1GAACES2CES1KMT2A | |
| SCHEMBL9382917 | 0.85 | CES1 (0.49) | GLO1GAACES2CES1KMT2A | |
| SCHEMBL9382912 | 0.85 | CES1 (0.49) | GLO1GAACES2CES1KMT2A | |
| SCHEMBL30770327 | 0.85 | CES2 (0.66) | GLO1GAACES2CES1KMT2A | |
| SCHEMBL9062780 | 0.85 | CES2 (0.66) | GLO1GAACES2CES1KMT2A | |
| SCHEMBL10864814 | 0.81 | GLO1 (0.49) | GLO1GAACES2KMT2AALDH1A1 | |
| SCHEMBL5263495 | 0.79 | ALDH1A1 (0.58) | GAACES2CES1KMT2AALDH1A1 | |
| SCHEMBL995357 | 0.79 | ALDH1A1 (0.58) | GAACES2CES1KMT2AALDH1A1 | |
| SCHEMBL995358 | 0.79 | ALDH1A1 (0.58) | GAACES2CES1KMT2AALDH1A1 | |
| SCHEMBL7435954 | 0.79 | GLO1 (0.75) | GLO1GAAKMT2AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620818-A1 | ARYL KETONES AS TESTOSTERONE 5$g(a)-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993013099-A1 | ARYL KETONES AS TESTOSTERONE 5α-REDUCTASE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-08 | — | — | WO | disclosed |