Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8489318 | 0.89 | CES2 (0.49) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL8489316 | 0.89 | CES2 (0.49) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL10861577 | 0.84 | ALDH1A1 (0.49) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL9382912 | 0.83 | CES1 (0.49) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL9382917 | 0.83 | CES1 (0.49) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL10864256 | 0.81 | MAPT (0.47) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL9385161 | 0.81 | GLO1 (0.58) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL9385166 | 0.81 | GLO1 (0.58) | GLO1CES2MAPTALDH1A1KMT2A | |
| SCHEMBL10863731 | 0.81 | MAPT (0.44) | GLO1MAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8494904 | 0.80 | MAPT (0.47) | GLO1MAPTALDH1A1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0168733-A2 | Process for the preparation of quinolinone and naphthyridoncarboxylic acids | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |