Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 1/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8536518 | 0.86 | ALDH1A1 (0.51) | TDP1L3MBTL1KCNH2HRH3MAPT | |
| SCHEMBL9611212 | 0.84 | MAPT (0.46) | TDP1L3MBTL1MAPTLMNACYP1A2 | |
| SCHEMBL18635927 | 0.83 | THRA (0.46) | TDP1L3MBTL1MAPTLMNACYP1A2 | |
| SCHEMBL9380023 | 0.83 | TDP1 (0.46) | TDP1L3MBTL1KCNH2HRH3MAPT | |
| SCHEMBL6701399 | 0.82 | TDP1 (0.74) | TDP1L3MBTL1KCNH2HRH3MAPT | |
| SCHEMBL4946581 | 0.81 | PKM (0.57) | L3MBTL1ALDH1A1 | |
| SCHEMBL12926245 | 0.81 | PRSS1 (0.46) | L3MBTL1MAPTLMNACYP1A2CYP3A4 | |
| SCHEMBL20629418 | 0.80 | TDP1 (0.46) | TDP1L3MBTL1MAPTLMNACYP1A2 | |
| SCHEMBL17431005 | 0.80 | LMNA (0.48) | L3MBTL1MAPTALDH1A1LMNACYP1A2 | |
| SCHEMBL7317389 | 0.80 | KCNH2 (0.56) | TDP1L3MBTL1KCNH2HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398426-B1 | Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA NV (BE) | 1994-03-09 | — | — | EP | disclosed |
| US-5070090-A | SUSTAINED RELEASE FROM CYCLODEXTRIN INCLUSION COMPOUND | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-12-03 | — | — | US | disclosed |
| EP-0398426-A1 | Antirhinoviral (thio)morpholinyl and piperazinyl alkylphenol ethers | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-11-22 | — | — | EP | disclosed |