Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031502 | 0.80 | GAA (0.44) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL6971403 | 0.80 | THRB (0.51) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL9085814 | 0.78 | MAPT (0.35) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL9381252 | 0.78 | MAPT (0.34) | ALDH1A1MAPTTP53SMN1; SMN2CTSB | |
| SCHEMBL6971401 | 0.77 | MAPT (0.39) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL9381034 | 0.76 | THRB (0.35) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL9379860 | 0.76 | MAPT (0.35) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL9383753 | 0.76 | MAPT (0.35) | ALDH1A1MAPTTP53SMN1; SMN2THRB | |
| SCHEMBL9380695 | 0.75 | MAPT (0.32) | MAPTSMN1; SMN2MALT1KMT2A | |
| SCHEMBL8051642 | 0.75 | MAPT (0.45) | ALDH1A1MAPTTP53SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0387195-B1 | Agents for the protection of plants against diseases | CIBA GEIGY AG (CH) | 1994-07-27 | — | — | EP | claimed |
| EP-0387195-B1 | Agents for the protection of plants against diseases | CIBA GEIGY AG (CH) | 1994-07-27 | — | — | EP | disclosed |
| US-5066661-A | Microbiocidal n-(cyanomethyl)-1,2,3-thiadiazole-7-carboxamides | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| US-5066661-A | Microbiocidal n-(cyanomethyl)-1,2,3-thiadiazole-7-carboxamides | CIBA-GEIGY CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| EP-0387195-A1 | Agents for the protection of plants against diseases | CIBA-GEIGY AG (CH) | 1990-09-12 | — | — | EP | disclosed |