Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031502 | 0.84 | GAA (0.44) | THRBGAAMAPTTP53SMN1; SMN2 | |
| SCHEMBL6971401 | 0.84 | MAPT (0.39) | THRBMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL8038913 | 0.83 | MAPT (0.40) | THRBMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL8051642 | 0.81 | MAPT (0.45) | THRBMAPTTP53SMN1; SMN2PDE10A | |
| SCHEMBL543646 | 0.81 | MAPT (0.49) | GAAMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL9087580 | 0.80 | LMNA (0.51) | MAPTTP53SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9385271 | 0.80 | EGLN1 (0.42) | THRBMAPTTP53SMN1; SMN2ALDH1A1 | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.80 | ALDH1A1 (0.44) | NPSR1MAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL7555956 | 0.78 | MAPT (0.39) | THRBMAPTTP53SMN1; SMN2ALDH1A1 | |
| SCHEMBL3743974 | 0.78 | PARP1 (0.40) | GAAMAPTTP53SMN1; SMN2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |