Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4031502 | 0.84 | GAA (0.44) | MAPTSMN1; SMN2TP53THRBMEN1 | |
| SCHEMBL6971403 | 0.84 | THRB (0.51) | MAPTSMN1; SMN2TP53THRBNPC1 | |
| SCHEMBL9087580 | 0.80 | LMNA (0.51) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| 1,2,3-Benzothia-Diazole-7-Carboxylic Acid SCHEMBL2455715 | 0.80 | ALDH1A1 (0.44) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL7555956 | 0.78 | MAPT (0.39) | MAPTSMN1; SMN2TP53THRBMEN1 | |
| SCHEMBL3743974 | 0.78 | PARP1 (0.40) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL73948 | 0.78 | MAPT (0.36) | MAPTSMN1; SMN2TP53THRBMEN1 | |
| SCHEMBL8051642 | 0.78 | MAPT (0.45) | MAPTSMN1; SMN2TP53THRBMEN1 | |
| SCHEMBL9087330 | 0.78 | GAA (0.49) | MAPTSMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL6964915 | 0.77 | MAPT (0.35) | MAPTSMN1; SMN2TP53THRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |