Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097075 | 0.86 | KDM4E (0.50) | ADRB3KDM4EALDH1A1HPGDGLA | |
| SCHEMBL11378558 | 0.83 | ADRB3 (0.41) | ADRB3 | |
| SCHEMBL433879 | 0.82 | KDM4E (0.42) | ADRB3KDM4EALDH1A1HPGDGLA | |
| SCHEMBL7091144 | 0.81 | DRD2 (0.47) | ADRB3KDM4E | |
| SCHEMBL8921162 | 0.80 | MAPT (0.43) | ADRB3KDM4EALDH1A1HPGDGLA | |
| SCHEMBL6579526 | 0.80 | TSHR (0.41) | ADRB3KDM4EALDH1A1HPGDGLA | |
| SCHEMBL96786 | 0.78 | ALDH1A1 (0.39) | ADRB3KDM4EALDH1A1HPGDGLA | |
| SCHEMBL96585 | 0.78 | MAOA (0.39) | ADRB3KDM4EALDH1A1HPGDGLA | |
| SCHEMBL11384757 | 0.77 | ADRB3 (0.37) | ADRB3HPGDCYP3A4 | |
| SCHEMBL8920419 | 0.77 | FLI1 (0.38) | ADRB3KDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | claimed |
| WO-1994003425-A2 | CARBOSTYRIL DERIVATIVES FOR THE TREATMENT OF ARRHYTHMIA | SYNTEX (U.S.A.) INC. (US) | 1994-02-17 | — | — | WO | disclosed |
| EP-0467325-A2 | Carbostyril derivatives | SYNTEX (U.S.A.) INC. (US) | 1992-01-22 | — | — | EP | disclosed |
| US-5082847-A | Antiarrhythmia | SYNTEX (U.S.A.) INC. (US) | 1992-01-21 | — | — | US | disclosed |
| US-4072683-A | BETA-ADRENERGIC BLOCKING AGENTS, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JA) | 1978-02-07 | — | — | US | disclosed |