Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543820 | 0.92 | RAB9A (0.62) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL9383480 | 0.89 | RAB9A (0.55) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL8546082 | 0.84 | RAB9A (0.54) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL9385263 | 0.84 | EGFR (0.41) | EGFRMEN1KMT2ASMN1; SMN2FDFT1 | |
| SCHEMBL8541109 | 0.83 | RAB9A (0.67) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL8542357 | 0.83 | RAB9A (0.58) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL8547151 | 0.82 | RAB9A (0.58) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL8545631 | 0.79 | MAPK14 (0.52) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL8549790 | 0.79 | RAB9A (0.54) | RAB9ANPC1TSHRL3MBTL1EGFR | |
| SCHEMBL9383475 | 0.78 | LMNA (0.58) | RAB9ANPC1TSHRL3MBTL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556375-A4 | NEMATICIDAL METHOD | DOWELANCO (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0556375-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-08-25 | — | — | EP | claimed |
| WO-1993004583-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-03-18 | — | — | WO | claimed |