Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546847 | 0.91 | RAB9A (0.41) | EGFRFDFT1SMN1; SMN2AURKARPS6KB1 | |
| SCHEMBL9383256 | 0.91 | TRPA1 (0.39) | EGFRALDH1A1KMT2APPARGLMNA | |
| SCHEMBL8548181 | 0.85 | TRPA1 (0.43) | EGFRKMT2ASMN1; SMN2LMNASLC2A1 | |
| SCHEMBL8547249 | 0.84 | AURKA (0.45) | EGFRSMN1; SMN2PPARGLMNAAURKA | |
| SCHEMBL9385472 | 0.84 | RAB9A (0.52) | EGFRFDFT1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8548684 | 0.79 | RAB9A (0.42) | ALDH1A1SMN1; SMN2LMNAAURKARPS6KB1 | |
| SCHEMBL8548239 | 0.79 | AURKA (0.44) | FDFT1ALDH1A1SMN1; SMN2PPARGSLC2A1 | |
| SCHEMBL9389676 | 0.78 | AURKA (0.41) | PPARAAURKARPS6KB1CSF1R | |
| SCHEMBL8548719 | 0.78 | MRGPRX1 (0.40) | ALDH1A1LMNAAURKARPS6KB1 | |
| SCHEMBL8546438 | 0.78 | CNR1 (0.38) | LMNAAURKARPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556375-A4 | NEMATICIDAL METHOD | DOWELANCO (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0556375-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-08-25 | — | — | EP | claimed |
| WO-1993004583-A1 | NEMATICIDAL METHOD | DOWELANCO (US) | 1993-03-18 | — | — | WO | claimed |