Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9393133 | 0.88 | TERT (0.48) | NQO1SMN1; SMN2HIF1ATOP2BCYP19A1 | |
| SCHEMBL9389590 | 0.84 | MEN1 (0.45) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL9388057 | 0.83 | ECE1 (0.52) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL9389584 | 0.82 | TOP2B (0.42) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL9389547 | 0.82 | KMT2A (0.49) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL7808985 | 0.81 | TOP2A (0.40) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL8796279 | 0.81 | TOP2A (0.46) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL11277491 | 0.81 | CYP19A1 (0.62) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL3418071 | 0.81 | CYP19A1 (0.62) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B | |
| SCHEMBL30513721 | 0.81 | CYP19A1 (0.62) | NQO1SMN1; SMN2HIF1ABRCA1TOP2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994005641-A1 | 4-SUBSTITUTED 6,9,-BIS (SUBSTITUTED-AMINO) BENZO [g] ISOQUINOLINE-5,10,DIONES | THE UNIVERSITY OF VERMONT (US) | 1994-03-17 | — | — | WO | claimed |
| WO-1994005641-A1 | 4-SUBSTITUTED 6,9,-BIS (SUBSTITUTED-AMINO) BENZO [g] ISOQUINOLINE-5,10,DIONES | THE UNIVERSITY OF VERMONT (US) | 1994-03-17 | — | — | WO | disclosed |