Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3381848 | 0.81 | PDPK1 (0.34) | KDM4E | |
| SCHEMBL30790326 | 0.81 | PDPK1 (0.34) | KDM4E | |
| SCHEMBL22121902 | 0.80 | SMN1; SMN2 (0.55) | HPGDSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL939047 | 0.79 | KDM4E (0.31) | HPGDSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL938864 | 0.76 | KDM4E (0.33) | HPGDKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL939452 | 0.75 | ALDH1A1 (0.34) | HPGDKDM4EMEN1KMT2ANPSR1 | |
| SCHEMBL22143229 | 0.73 | HPGD (0.48) | HPGDSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL15688384 | 0.73 | HPGD (0.48) | HPGDSMN1; SMN2KDM4EPOLBMAPT | |
| SCHEMBL16441562 | 0.71 | COMT (0.32) | — | |
| SCHEMBL603330 | 0.67 | ENPP3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2186410-B1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-7875606-B2 | Herbicides; selectivity between crops and weeds | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-01-25 | — | — | US | disclosed |
| EP-1364946-B1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-24 | — | — | EP | disclosed |
| US-7833939-B2 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-11-16 | — | — | US | disclosed |
| EP-1405853-B1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2010-11-03 | — | — | EP | disclosed |
| EP-2186410-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-05-19 | — | — | EP | disclosed |
| US-7238689-B2 | Isoxazoline derivative and herbicide comprising the same as active ingredient | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-03 | — | — | US | disclosed |
| US-20050256004-A1 | Herbicide compositions | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| US-20040259734-A1 | Izoxazoline derivative and herbicide | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-12-23 | — | — | US | disclosed |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
| EP-1405853-A1 | ISOXAZOLINE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-04-07 | — | — | EP | disclosed |
| EP-1364946-A1 | ISOXAZOLINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2003-11-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256004-A1 | Herbicide compositions | DDT, CYP4X1, GLRX3 | HPGD 3341/4885SMN1; SMN2 3621/4885KDM4E 1984/4885 |
| US-20040259734-A1 | Izoxazoline derivative and herbicide | HCN4, HDHD5, KCNJ1 | HPGD 3501/4885SMN1; SMN2 4744/4885KDM4E 1164/4885 |
| US-20040110749-A1 | Isoxazoline derivative and herbicide comprising the same as active ingredient | CYP4X1, PRDX5, CYP3A7 | HPGD 1897/4885SMN1; SMN2 3882/4885KDM4E 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.