SCHEMBL93888

SCHEMBL93888

CCCCCCCCCCCCCCCC(=O)O[C@]1(C(=O)CO)[C@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 13/20 0.95
PGR P06401 4/20 0.95
CYP3A4 P08684 4/20 0.95
USP2 O75604 3/20 0.95
MEN1 O00255 1/20 0.95
KMT2A Q03164 1/20 0.95
MMP1 P03956 10/20 0.79
LMNA P02545 2/20 0.72
NR1I2 O75469 2/20 0.72
MAPT P10636 2/20 0.72
MLNR O43193 1/20 0.72
ABCB11 O95342 1/20 0.72
CYP3A5 P20815 1/20 0.72
PPARG P37231 1/20 0.72
SMN1; SMN2 Q16637 1/20 0.72
NPSR1 Q6W5P4 1/20 0.72
CYP2D6 P10635 1/20 0.72
CYP2C9 P11712 1/20 0.72
ADORA3 P0DMS8 1/20 0.71
DRD2 P14416 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5151466 1.00 NR3C1 (0.95) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL2933726 1.00 NR3C1 (0.95) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL2933292 1.00 NR3C1 (0.95) NR3C1PGRCYP3A4USP2MEN1
SCHEMBL2940259 1.00 NR3C1 (0.95) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL14339607 0.98 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL16243364 0.98 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL9768484 0.98 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL11051241 0.98 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Dexamethasone Valarate SCHEMBL124723 0.98 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1
Betamethasone Valerate SCHEMBL14339612 0.98 NR3C1 (1.00) NR3C1PGRCYP3A4USP2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1916 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122079802-A Cationic lipids and compositions thereof 2026-05-26 CN claimed
US-12611381-B2 Cationic hyaluronic acid coated spanlastics and preparation and application thereof FBC (SHANGHAI) PHARMACEUTICAL TECHNOLOGY CO., LTD. (CN) 2026-04-28 US claimed
US-20260108657-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS INSIGNIA PHARMACEUTICALS, LLC (US) 2026-04-23 US claimed
EP-3253365-B1 POLYAPHRONS AND PALPEBRAL ADMINISTRATION THEREOF SANTEN PHARMACEUTICAL CO LTD (JP) 2026-02-18 EP claimed
US-12491289-B2 Pharmaceutical compositions for treating osteoarthritis INSIGNIA PHARMACEUTICALS, LLC (US) 2025-12-09 US claimed
EP-4654956-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS Insignia Pharmaceuticals, LLC (US) 2025-12-03 EP claimed
US-20250352666-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF GENERATION BIO CO (US) 2025-11-20 US claimed
EP-4626409-A1 SYNTHETIC SINGLE STRANDED NUCLEIC ACID COMPOSITIONS AND METHODS THEREOF Generation Bio Co. (US) 2025-10-08 EP claimed
US-20250295608-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS INSIGNIA PHARMACEUTICALS, LLC (US) 2025-09-25 US claimed
US-20250288599-A1 PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING OSTEOARTHRITIS INSIGNIA PHARMACEUTICALS, LLC (US) 2025-09-18 US claimed
US-20070280995-A1 Use of a steroid prodrug for the treatment of disease of the posterior segment of the eye NOVAGALI PHARMA SA (FR) 2007-12-06 US claimed
WO-2007083316-A2 MICROSPHERES COMPRISING NANOCAPSULES CONTAINING A LIPOPHILIC DRUG YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) 2007-07-26 WO claimed
WO-2003043602-A1 SOLID DISPERSIONS CONTAINING SUBSTITUTED CYCLODEXTRIN AND INSOLUBLE DRUG AND THEIR PREPARATIONS KOREA DDS PHARMACEUTICAL CO., LTD. (KR) 2003-05-30 WO claimed
EP-1009409-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OCULAR INFLAMMATIONS COMPRISING DEXAMETHASONE PALMITATE Pharmateam Development Ltd. (IL) 2000-06-21 EP claimed
WO-1999011270-A1 PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF OCULAR INFLAMMATIONS COMPRISING DEXAMETHASONE PALMITATE PHARMATEAM DEVELOPMENT LTD. (IL) 1999-03-11 WO claimed
US-5811547-A Method for inducing crystalline state transition in medicinal substance NIPPON SHINYAJU CO., LTD. (JP) 1998-09-22 US claimed
EP-0041772-B2 FAT EMULSION CONTAINING A STEROID GREEN CROSS CORPORATION (JP) 1990-04-18 EP claimed
EP-0041772-B1 FAT EMULSION CONTAINING A STEROID GREEN CROSS CORPORATION (JP) 1984-10-17 EP claimed
US-4340594-A Fat emulsion containing steroid THE GREEN CROSS CORPORATION (JP) 1982-07-20 US claimed
EP-0041772-A2 Fat emulsion containing a steroid GREEN CROSS CORPORATION (JP) 1981-12-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12611381-B2 Cationic hyaluronic acid coated spanlastics and preparation and application thereof LIPA, CD44, HPSE NR3C1 70/4885PGR 463/4885CYP3A4 1890/4885
US-20250352666-A1 LIPID NANOPARTICLE COMPOSITIONS AND USES THEREOF LIPA, EYA3, EYA2 NR3C1 2356/4885PGR 1929/4885CYP3A4 4870/4885
US-20260108657-A1 PHARMACEUTICAL COMPOSITIONS FOR TREATING OSTEOARTHRITIS CD44, COL2A1, PPARD NR3C1 29/4885PGR 140/4885CYP3A4 1665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.