Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 13/20 | 0.56 |
| ▸ | DDO | Q99489 | 6/20 | 0.56 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.36 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.36 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9387834 | 0.81 | DAO (0.46) | DAODDO | |
| SCHEMBL3362656 | 0.79 | DAO (0.61) | DAODDOERCC1ERCC4 | |
| SCHEMBL9393007 | 0.76 | GRIN2D (0.49) | DAODDO | |
| SCHEMBL9389006 | 0.76 | DAO (0.54) | DAODDO | |
| SCHEMBL9389846 | 0.76 | DAO (0.49) | DAODDO | |
| SCHEMBL9388997 | 0.76 | DAO (0.66) | DAODDOPBK | |
| SCHEMBL9387612 | 0.76 | DAO (0.66) | DAODDO | |
| SCHEMBL311827 | 0.73 | ADORA2A (0.39) | — | |
| SCHEMBL3360159 | 0.72 | DAO (0.58) | DAODDOERCC1ERCC4 | |
| SCHEMBL3424908 | 0.72 | DAO (0.53) | DAODDOPBK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |