Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 14/20 | 0.53 |
| ▸ | DDO | Q99489 | 8/20 | 0.53 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3362656 | 0.88 | DAO (0.61) | DAODDO | |
| SCHEMBL3421760 | 0.81 | DAO (0.55) | DAODDONEK1 | |
| SCHEMBL3360159 | 0.80 | DAO (0.58) | DAODDOKDM4EHSD17B10ALDH1A1 | |
| SCHEMBL3360150 | 0.75 | DAO (0.59) | DAODDOHSD17B10ALDH1A1 | |
| SCHEMBL22408523 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1HPGD | |
| SCHEMBL9388997 | 0.73 | DAO (0.66) | DAODDOPBKKDM4E | |
| SCHEMBL3361211 | 0.73 | DAO (0.53) | DAODDO | |
| SCHEMBL20505032 | 0.73 | IDO1 (0.65) | KDM4EHPGD | |
| SCHEMBL3432805 | 0.73 | DAO (0.67) | DAODDOHSD17B10 | |
| SCHEMBL3363037 | 0.73 | DAO (0.61) | DAODDO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010058314-A1 | HYDROXYQUINOLIN-2(1H)-ONES AND DERIVATIVES THEREOF | PFIZER INC. (US) | 2010-05-27 | — | — | WO | claimed |