Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 6/20 | 0.49 |
| ▸ | CTSK | P43235 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 6/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9388996 | 1.00 | CTSS (0.49) | CTSSCTSKOPRM1CTSLCTSB | |
| SCHEMBL12126314 | 0.88 | ACE (0.60) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL22695725 | 0.86 | CTSS (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL16656682 | 0.86 | CTSS (0.54) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL30881100 | 0.86 | CTSS (0.52) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL22199401 | 0.85 | CTSS (0.50) | CTSSCTSKOPRM1CTSLCTSB | |
| SCHEMBL15840456 | 0.85 | CTSL (0.54) | CTSSCTSKOPRM1CTSLCTSB | |
| SCHEMBL6893021 | 0.84 | CTSS (0.51) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL6927203 | 0.84 | CTSS (0.48) | CTSSCTSKCTSLCTSBACE | |
| SCHEMBL22317109 | 0.83 | CTSS (0.52) | CTSSCTSKCTSLCTSBACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017020972-A1 | PYRROLOBENZODIAZEPINE-ANTIBODY CONJUGATES | VAN BERKEL, Patricius Hendrikus Cornelis (CH) | 2017-02-09 | — | — | WO | disclosed |
| WO-1994009031-A1 | ANALOGUES OF CHOLECYSTOKININ (30-33) CONTAINING AN ALPHA-SUBSTITUTED AMINOACID | WARNER-LAMBERT COMPANY (US) | 1994-04-28 | — | — | WO | disclosed |