Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 4/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | FCER2 | P06734 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | MME | P08473 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126308 | 0.88 | ACE (0.55) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL12126314 | 0.88 | ACE (0.60) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL22927776 | 0.87 | CTSS (0.67) | CTSSCTSLCTSBCTSKMMP1 | |
| SCHEMBL22695725 | 0.86 | CTSS (0.54) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL16656682 | 0.86 | CTSS (0.54) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL25976737 | 0.86 | CTSS (0.55) | CTSSCTSLCTSBCTSKMMP1 | |
| SCHEMBL30881100 | 0.86 | CTSS (0.52) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL9388987 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL9388996 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSKACE | |
| SCHEMBL18752348 | 0.85 | MMP1 (0.46) | CTSSCTSLCTSBCTSKMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006084-A1 | ANTI-DLL3 ANTIBODY AND PREPARATION METHOD THEREFOR, DRUG CONJUGATE AND APPLICATION THEREOF | 上海复旦张江生物医药股份有限公司 | 2023-02-02 | — | — | WO | disclosed |
| WO-2020254613-A1 | CONTROLLED-RELEASE TYROSINE KINASE INHIBITOR COMPOUNDS WITH LOCALIZED PK PROPERTIES | Ascendis Pharma Oncology Division A/S (DK) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020254611-A1 | ANTI-CTLA4 CONJUGATES | Ascendis Pharma Oncology Division A/S (DK) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020254617-A1 | ANTI-CTLA4 COMPOUNDS WITH LOCALIZED PK PROPERTIES | Ascendis Pharma Oncology Division A/S (DK) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020254609-A1 | TYROSINE KINASE INHIBITOR CONJUGATES | Ascendis Pharma Oncology Division A/S (DK) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020141225-A1 | MINIMIZATION OF SYSTEMIC INFLAMMATION | ASCENDIS PHARMA A/S (DK) | 2020-07-09 | — | — | WO | disclosed |