Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.52 |
| ▸ | CTSK | P43235 | 5/20 | 0.52 |
| ▸ | CTSL | P07711 | 7/20 | 0.50 |
| ▸ | CTSB | P07858 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126314 | 0.89 | ACE (0.60) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL22695725 | 0.87 | CTSS (0.54) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL16656682 | 0.87 | CTSS (0.54) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL22175312 | 0.87 | CYP3A4 (0.68) | CTSSCTSKCTSLCTSBCYP3A4 | |
| SCHEMBL22317109 | 0.87 | CTSS (0.52) | CTSSCTSKCTSLCTSBL3MBTL1 | |
| SCHEMBL16254357 | 0.87 | CTSS (0.52) | CTSSCTSKCTSLCTSBL3MBTL1 | |
| SCHEMBL22199401 | 0.86 | CTSS (0.50) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL9388987 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL9388996 | 0.86 | CTSS (0.49) | CTSSCTSKCTSLCTSBALDH1A1 | |
| SCHEMBL6927203 | 0.84 | CTSS (0.48) | CTSSCTSKCTSLCTSBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240092740-A1 | 4-HYDROXYBENZOMORPHANS | RENSSELAER POLYTECHNIC INSTITUTE (US) | 2024-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092740-A1 | 4-HYDROXYBENZOMORPHANS | HTR3C, OPRL1, OPRK1 | CTSS 3282/4885CTSK 4288/4885CTSL 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.