Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 9/20 | 0.45 |
| ▸ | DDO | Q99489 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583717 | 0.80 | DAO (0.66) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9390027 | 0.77 | DAO (0.68) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9389395 | 0.76 | KDM4E (0.46) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9389416 | 0.76 | DAO (0.66) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9388997 | 0.76 | DAO (0.66) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9393346 | 0.76 | DAO (0.49) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9389819 | 0.76 | KIF11 (0.47) | DAODDOKDM4ETDP1PLA2G7 | |
| SCHEMBL9389042 | 0.76 | DAO (0.36) | DAODDOTRPV1 | |
| SCHEMBL9392651 | 0.76 | DAO (0.49) | DAODDOKDM4ETDP1CA1 | |
| SCHEMBL9387636 | 0.74 | DAO (0.55) | DAODDOKDM4ETDP1PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |