Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 8/20 | 0.45 |
| ▸ | DDO | Q99489 | 5/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583717 | 0.80 | DAO (0.66) | KDM4EALDH1A1LMNAPOLBHPGD | |
| SCHEMBL9390027 | 0.77 | DAO (0.68) | KDM4EALDH1A1LMNADAODDO | |
| SCHEMBL9389416 | 0.76 | DAO (0.66) | KDM4EDAODDOTDP1PLA2G7 | |
| SCHEMBL9389395 | 0.76 | KDM4E (0.46) | KDM4EDAODDOTDP1PLA2G7 | |
| SCHEMBL9393346 | 0.76 | DAO (0.49) | KDM4EALDH1A1LMNAHPGDDAO | |
| SCHEMBL9388997 | 0.76 | DAO (0.66) | KDM4ELMNADAODDOTDP1 | |
| SCHEMBL9389023 | 0.76 | DAO (0.45) | KDM4EALDH1A1LMNAHPGDHTT | |
| SCHEMBL9387636 | 0.74 | DAO (0.55) | KDM4EALDH1A1LMNAHPGDDAO | |
| SCHEMBL9389330 | 0.73 | KDM4E (0.43) | KDM4EDAODDOTDP1PLA2G7 | |
| SCHEMBL16154714 | 0.72 | KIF11 (0.54) | KIF11KDM4EALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007500-A1 | 2,5-DIHYDRO-2,5-DIOXO-1H-AZEPINES AND 2,5-DIHYDRO-2-OXO-1H-AZEPINES AND THE USE THEREOF AS EXCITATORY AMINO ACID AND GLYCINE RECEPTOR ANTAGONISTS | WEBER ECKARD (US) | 1994-04-14 | — | — | WO | disclosed |