Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386679 | 0.89 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1MAPTRXFP1 | |
| SCHEMBL6584578 | 0.87 | KDM4E (0.42) | KDM4EHSD17B10ALDH1A1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL5734972 | 0.82 | KDM4E (0.46) | KDM4EHSD17B10ALDH1A1MAPTRXFP1 | |
| SCHEMBL6582992 | 0.81 | ALDH1A1 (0.41) | KDM4EHSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL9555823 | 0.79 | ALDH1A1 (0.44) | KDM4EHSD17B10ALDH1A1MAPTTDP1 | |
| SCHEMBL9556162 | 0.79 | KDM4E (0.51) | KDM4EHSD17B10ALDH1A1MAPTMAPK1 | |
| SCHEMBL6580601 | 0.77 | ALDH1A1 (0.46) | KDM4EHSD17B10ALDH1A1MAPTRXFP1 | |
| SCHEMBL9216843 | 0.76 | KDM4E (0.55) | KDM4EHSD17B10ALDH1A1MAPTUSP2 | |
| SCHEMBL23882575 | 0.74 | KDM4E (0.58) | KDM4EHSD17B10ALDH1A1RXFP1USP2 | |
| SCHEMBL2180069 | 0.74 | RAB9A (0.63) | KDM4EALDH1A1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994007869-A1 | QUINAZOLINE DERIVATIVES | ZENECA LIMITED (GB) | 1994-04-14 | — | — | WO | disclosed |