Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | AGER | Q15109 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28387489 | 0.72 | SMN1; SMN2 (0.48) | KMT2ASMN1; SMN2ALOX15TSHRMEN1 | |
| SCHEMBL711690 | 0.71 | POLB (0.45) | EPHX1KMT2ASMN1; SMN2AGERALOX15 | |
| SCHEMBL8937433 | 0.65 | ALOX15 (0.56) | ALOX15TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL765653 | 0.64 | ALDH1A1 (0.49) | KMT2ACYP2C9CYP2C19MEN1NPSR1 | |
| SCHEMBL196518 | 0.64 | SRD5A2 (0.62) | KMT2ASMN1; SMN2MEN1ALDH1A1MAPT | |
| SCHEMBL3167031 | 0.64 | ALDH1A1 (0.41) | KMT2ACYP2C9CYP2C19MEN1NPSR1 | |
| 4-Chloro-Benzoic Acid SCHEMBL28417247 | 0.63 | TSHR (0.59) | EPHX1KMT2ASMN1; SMN2AGERALOX15 | |
| SCHEMBL7070720 | 0.62 | ALOX15 (0.52) | KMT2ASMN1; SMN2ALOX15TSHRKDM4E | |
| SCHEMBL6938875 | 0.62 | NR4A1 (0.59) | KMT2ASMN1; SMN2ALOX15TSHRCYP2C19 | |
| SCHEMBL9439212 | 0.62 | ALDH1A1 (0.54) | ALOX15TSHRKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994014765-A1 | CYCLOHEXYLSULFONYL-ACRYLIC ACID AND ITS DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1994-07-07 | — | — | WO | claimed |
| WO-1994014765-A1 | CYCLOHEXYLSULFONYL-ACRYLIC ACID AND ITS DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 1994-07-07 | — | — | WO | disclosed |