Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 11/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389285 | 0.94 | KCNJ1 (0.60) | KCNJ1SIGMAR1KCNH2LMNAHRH3 | |
| SCHEMBL9384677 | 0.86 | HRH3 (0.54) | LMNAHRH3KDM4EALDH1A1PKM | |
| SCHEMBL9428657 | 0.84 | LMNA (0.51) | SIGMAR1LMNAKDM4EALDH1A1PKM | |
| SCHEMBL9383628 | 0.81 | KCNJ1 (0.63) | KCNJ1SIGMAR1KCNH2HRH3ALDH1A1 | |
| SCHEMBL9384376 | 0.78 | KCNJ1 (0.58) | KCNJ1SIGMAR1KCNH2HRH3ALDH1A1 | |
| SCHEMBL9384842 | 0.78 | KCNJ1 (0.58) | KCNJ1SIGMAR1KCNH2HRH3ALDH1A1 | |
| SCHEMBL9428430 | 0.78 | SMN1; SMN2 (0.60) | KCNJ1KCNH2LMNAKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9384359 | 0.77 | KCNJ1 (0.57) | KCNJ1SIGMAR1KCNH2HRH3ALDH1A1 | |
| SCHEMBL9389722 | 0.77 | MAPT (0.46) | SIGMAR1LMNAKDM4EALDH1A1PKM | |
| Oxalic Acid SCHEMBL9388424 | 0.77 | KCNJ1 (0.57) | KCNJ1SIGMAR1KCNH2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |