Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | HRH2 | P25021 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389552 | 0.86 | KCNJ1 (0.59) | HRH3ALDH1A1KDM4EPKMLMNA | |
| SCHEMBL9429332 | 0.85 | DRD2 (0.53) | HRH3HRH2HRH1LMNADRD3 | |
| SCHEMBL9428545 | 0.85 | HTR1A (0.56) | HRH1ALDH1A1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL9389285 | 0.84 | KCNJ1 (0.60) | HRH3LMNA | |
| SCHEMBL9383669 | 0.82 | HRH3 (0.57) | HRH3HRH2HRH1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9383594 | 0.81 | HRH3 (0.56) | HRH3HRH2HRH1ALDH1A1KDM4E | |
| SCHEMBL9385515 | 0.81 | ALDH1A1 (0.47) | HRH3ALDH1A1KDM4ESMN1; SMN2PKM | |
| Oxalic Acid SCHEMBL9388883 | 0.79 | ALDH1A1 (0.46) | ALDH1A1KDM4ESMN1; SMN2MAPTLMNA | |
| SCHEMBL9385412 | 0.79 | HRH3 (0.62) | HRH3HRH2HRH1ALDH1A1KDM4E | |
| SCHEMBL521113 | 0.78 | HRH3 (0.71) | HRH3HRH2HRH1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369627-B1 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5008267-A | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1991-04-16 | — | — | US | disclosed |
| EP-0369627-A2 | Pyrimidinedione derivative compounds, method of producing the same and antiarrythmic agents containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-05-23 | — | — | EP | disclosed |