SCHEMBL939103

SCHEMBL939103

CC=[Zr]C(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
HTR2A P28223 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
CHRM2 P08172 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CHRM1 P11229 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA2B P18089 1/20 0.33
ADRA2C P18825 1/20 0.33
NFKB1 P19838 1/20 0.33
CHRM3 P20309 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
THPO P40225 1/20 0.33
OPRK1 P41145 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8568817 0.77 HTR2A (0.34) HTR2AHTR6SIGMAR1
SCHEMBL29843950 0.76 HTR6 (0.32) HTR2AHTR6SIGMAR1
SCHEMBL8677603 0.76 HTR6 (0.33) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL5597184 0.74 SIGMAR1 (0.41) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL29603716 0.74 SIGMAR1 (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL668104 0.74 SIGMAR1 (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL28003595 0.74 SIGMAR1 (0.38) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL29658875 0.74 SIGMAR1 (0.41) KDM4EHTR2ALMNATP53CHRM2
SCHEMBL8384388 0.73 HTR6 (0.31) HTR2AHTR6SIGMAR1
SCHEMBL7711844 0.73 SIGMAR1 (0.35) KDM4EHTR2ALMNATP53CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3609483-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY Urigen Pharmaceuticals, Inc. (US) 2020-02-19 EP disclosed
WO-2018191412-A9 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2019-05-31 WO disclosed
WO-2018191412-A1 ARTICLE OF MANUFACTURE COMPRISING LOCAL ANESTHETIC, BUFFER, AND GLYCOSAMINOGLYCAN IN SYRINGE WITH IMPROVED STABILITY URIGEN PHARMACEUTICALS, INC. (US) 2018-10-18 WO disclosed
US-8394737-B2 Preparation of activating supports TOTAL PETROCHEMICALS RESEARCH FELUY Seneffe (BE) 2013-03-12 US disclosed
US-20110009582-A1 Preparation of Activating Supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2011-01-13 US disclosed
EP-2170511-A1 PREPARATION OF ACTIVATING SUPPORTS Total Petrochemicals Research Feluy (BE) 2010-04-07 EP disclosed
EP-2025403-A1 Preparation of activating supports TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-02-18 EP disclosed
WO-2009013197-A1 PREPARATION OF ACTIVATING SUPPORTS TOTAL PETROCHEMICALS RESEARCH FELUY (BE) 2009-01-29 WO disclosed
EP-0426853-B2 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI CHEMICALS INC (JP) 2000-03-29 EP disclosed
US-5969049-A Process for preparing propylene polymer composition and propylene polymer composition MITSUI CHEMICALS, INC. (JP) 1999-10-19 US disclosed
US-5292811-A Crystalline propylene polymer, amorphous ethylene-alpha-olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
US-5126301-A Organometallic compound, aluminoxane, group 4 metal compound, and olefin polymer MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) 1992-06-30 US disclosed
EP-0469153-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-02-05 EP disclosed
EP-0426853-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
EP-0427567-A2 Parabolic antenna reflector and process for preparing same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-05-15 EP disclosed
EP-0409992-A1 PROCESS FOR PRODUCING THERMOPLASTIC ELASTOMER MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-30 EP disclosed
EP-0406912-A2 Process for polymerizing olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-09 EP disclosed
EP-0294942-A1 Solid catalyst for polymerizing an olefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-12-14 EP disclosed
EP-0285443-A1 Process for producing solid catalyst for polymerization of olefins MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-10-05 EP disclosed
EP-0283164-A2 Cyclo-olefinic random copolymer, olefinic random copolymer, and process for producing cyclo-olefinic random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-09-21 EP disclosed