Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SPR | P35270 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392502 | 0.87 | ALDH1A1 (0.48) | HSD17B10CASP1ALDH1A1TSHRSPR | |
| SCHEMBL9393900 | 0.85 | TSHR (0.52) | HSD17B10CASP1ALDH1A1TSHRSPR | |
| SCHEMBL9394558 | 0.85 | SPR (0.54) | HSD17B10CASP1ALDH1A1MAPTTSHR | |
| SCHEMBL9396882 | 0.84 | ALDH1A1 (0.56) | HSD17B10ALDH1A1MAPTTSHRSPR | |
| SCHEMBL1388066 | 0.83 | RAB9A (0.55) | ALDH1A1MAPTPOLBTSHRSMN1; SMN2 | |
| SCHEMBL9285642 | 0.83 | ALDH1A1 (0.45) | HSD17B10CASP1ALDH1A1MAPTTSHR | |
| SCHEMBL9396836 | 0.83 | AVPR2 (0.47) | HSD17B10CASP1AVPR2ALDH1A1TSHR | |
| SCHEMBL9393919 | 0.83 | ALDH1A1 (0.44) | HSD17B10CASP1AVPR2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9394536 | 0.82 | AVPR2 (0.46) | HSD17B10CASP1AVPR2ALDH1A1MAPT | |
| SCHEMBL9396870 | 0.82 | ALDH1A1 (0.47) | HSD17B10CASP1ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994029295-A1 | HETEROCYCLIC DERIVATIVES WITH IMMUNOMODULATING ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-22 | — | — | WO | disclosed |