Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9392502 | 0.88 | ALDH1A1 (0.48) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 | |
| SCHEMBL9394558 | 0.86 | SPR (0.54) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 | |
| SCHEMBL9393900 | 0.86 | TSHR (0.52) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 | |
| SCHEMBL9396882 | 0.85 | ALDH1A1 (0.56) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 | |
| SCHEMBL9396836 | 0.84 | AVPR2 (0.47) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 | |
| SCHEMBL1388066 | 0.84 | RAB9A (0.55) | ALDH1A1TSHRRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL9272515 | 0.83 | NOTUM (0.44) | ALDH1A1RAB9ASMN1; SMN2KMT2ASLC22A12 | |
| SCHEMBL9712284 | 0.83 | NOTUM (0.44) | ALDH1A1RAB9ASMN1; SMN2HPGDNPC1 | |
| Hydrochloric Acid SCHEMBL9394536 | 0.83 | AVPR2 (0.46) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 | |
| SCHEMBL9393885 | 0.83 | HSD17B10 (0.47) | ALDH1A1TSHRSPRRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639182-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992018483-A1 | QUINOLINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-29 | — | — | WO | disclosed |