Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394261 | 0.85 | TSHR (0.48) | TSHRCTSLCTSBCTSKNAAA | |
| SCHEMBL5787333 | 0.83 | OPRL1 (0.49) | OPRL1POLB | |
| SCHEMBL599216 | 0.82 | TSHR (0.45) | TSHRCTSLCTSBCTSKNAAA | |
| SCHEMBL31034964 | 0.80 | TRPV6 (0.42) | TSHRCTSLCTSBCTSKTAAR1 | |
| SCHEMBL1613917 | 0.78 | TSHR (0.48) | TSHRCTSLCTSBCTSKNAAA | |
| SCHEMBL7936478 | 0.77 | AGTR2 (0.45) | TSHRCTSLCTSBCTSKNAAA | |
| SCHEMBL20284995 | 0.77 | OPRL1 (0.51) | CTSLCTSBCTSKTACR1OPRL1 | |
| SCHEMBL20455696 | 0.76 | OPRM1 (0.42) | CTSLCTSBCTSKOPRL1 | |
| SCHEMBL25631052 | 0.75 | TAAR1 (0.47) | TSHRCTSLCTSBCTSKNAAA | |
| SCHEMBL5790770 | 0.75 | CTSL (0.48) | TSHRCTSLCTSBCTSKNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113636977-B | Synthesis method of 2-aryl benzazepine and derivatives thereof | 温州大学 | 2022-12-20 | — | — | CN | disclosed |
| CN-113636977-A | Synthesis method of 2-aryl benzazepine and derivatives thereof | 温州大学 | 2021-11-12 | — | — | CN | disclosed |