Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | CASP1 | P29466 | 4/20 | 0.49 |
| ▸ | CASP7 | P55210 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888893 | 0.84 | MEN1 (0.56) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL29282173 | 0.84 | MEN1 (0.68) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL29202682 | 0.84 | MEN1 (0.56) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL29202622 | 0.83 | ACHE (0.46) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL29202644 | 0.83 | KDM4E (0.52) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL29202651 | 0.81 | KMT2A (0.57) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL29202709 | 0.81 | ALDH1A1 (0.57) | KDM4EKMT2AMEN1MAPTLMNA | |
| SCHEMBL18655577 | 0.80 | MAPT (0.67) | KDM4ERXFP1KMT2AMEN1MAPT | |
| SCHEMBL29282174 | 0.79 | KDM4E (0.49) | KDM4ERXFP1KMT2AMEN1NR1I2 | |
| SCHEMBL19271263 | 0.79 | MAPT (0.65) | KDM4ERXFP1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117987851-A | Method for preparing indolo [2,3-b ] quinoline compounds by electrochemical iodine catalysis | 山东第二医科大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-117946104-A | Preparation method of iodine-mediated indolo [2,3-b ] quinoline compound in water phase | 山东第二医科大学 | 2024-04-30 | — | — | CN | disclosed |
| WO-2015147666-A1 | N-GUANYL DERIVATIVES OF 9-AMINO-5.1 1 -DIMETHYL-5H-INDOLO[2,3-B]QUINOLINE HAVING CYTOTOXIC ACTIVITY | INSTYTUT FARMACEUTYCZNY (PL) | 2015-10-01 | — | — | WO | disclosed |
| WO-1994018203-A1 | ALKALOID COMPOUNDS EXTRACTED FROM CRYPTOLEPIS SANQUINOLENTA AND USES THEREOF | HEALTHSEARCH, INC. (US) | 1994-08-18 | — | — | WO | disclosed |