Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9394688 | 0.83 | KDM4E (0.59) | ACHELMNAL3MBTL1GPR3KDM4E | |
| SCHEMBL29202644 | 0.82 | KDM4E (0.52) | LMNAL3MBTL1KDM4ERXFP1MEN1 | |
| SCHEMBL29202682 | 0.75 | MEN1 (0.56) | LMNAL3MBTL1GPR3KDM4ERXFP1 | |
| SCHEMBL30888893 | 0.75 | MEN1 (0.56) | LMNAL3MBTL1GPR3KDM4ERXFP1 | |
| SCHEMBL1923381 | 0.72 | GPR3 (0.64) | ACHELMNAL3MBTL1GPR3KDM4E | |
| SCHEMBL8011931 | 0.72 | GPR3 (0.64) | ACHELMNAL3MBTL1GPR3KDM4E | |
| SCHEMBL29202709 | 0.71 | ALDH1A1 (0.57) | ACHELMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL8832401 | 0.70 | MEN1 (0.57) | LMNAL3MBTL1KDM4EMEN1KMT2A | |
| SCHEMBL13562245 | 0.70 | ALKBH5 (0.51) | ACHELMNAL3MBTL1GPR3KDM4E | |
| SCHEMBL17033924 | 0.70 | KDM4E (0.43) | LMNAKDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117987851-A | Method for preparing indolo [2,3-b ] quinoline compounds by electrochemical iodine catalysis | 山东第二医科大学 | 2024-05-07 | — | — | CN | disclosed |
| CN-117946104-A | Preparation method of iodine-mediated indolo [2,3-b ] quinoline compound in water phase | 山东第二医科大学 | 2024-04-30 | — | — | CN | disclosed |