Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.56 |
| ▸ | AHR | P35869 | 1/20 | 0.56 |
| ▸ | PDE2A | O00408 | 1/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 2/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30888893 | 1.00 | MEN1 (0.56) | MEN1KMT2ANR1I2AHRPDE2A | |
| SCHEMBL9394688 | 0.84 | KDM4E (0.59) | MEN1KMT2ANR1I2AHRPDE2A | |
| SCHEMBL29282173 | 0.82 | MEN1 (0.68) | MEN1KMT2ANR1I2AHRPDE2A | |
| SCHEMBL29202709 | 0.81 | ALDH1A1 (0.57) | MEN1KMT2APDE2APDE3BPDE3A | |
| SCHEMBL29202622 | 0.75 | ACHE (0.46) | MEN1KMT2ANR1I2AHRKDM4E | |
| SCHEMBL20370885 | 0.73 | GPR3 (0.53) | MEN1KMT2ANR1I2AHRKDM4E | |
| SCHEMBL29282175 | 0.73 | ALKBH5 (0.50) | MEN1KMT2ANR1I2AHRKDM4E | |
| SCHEMBL8832163 | 0.72 | MEN1 (1.00) | MEN1KMT2ANR1I2AHRKDM4E | |
| SCHEMBL16625722 | 0.71 | GPR3 (0.50) | MEN1KMT2ANR1I2AHRKDM4E | |
| SCHEMBL12249979 | 0.71 | ALKBH5 (0.56) | MEN1KMT2ANR1I2AHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946104-A | Preparation method of iodine-mediated indolo [2,3-b ] quinoline compound in water phase | 山东第二医科大学 | 2024-04-30 | — | — | CN | disclosed |