SCHEMBL9395385

SCHEMBL9395385

N#CC(C#N)=C(c1cccs1)c1cccs1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
DAO P14920 1/20 0.45
NPC1 O15118 5/20 0.42
RAB9A P51151 5/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
ALDH1A1 P00352 3/20 0.42
POLB P06746 2/20 0.42
LMNA P02545 2/20 0.42
HDAC1 Q13547 1/20 0.42
HPGDS O60760 1/20 0.39
GSK3B P49841 1/20 0.39
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.38
ATM Q13315 1/20 0.38
HPGD P15428 2/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11424654 0.88 HPGDS (0.52) CES2CES1DAONPC1RAB9A
SCHEMBL8631890 0.81 CES2 (0.45) CES2CES1DAONPC1RAB9A
SCHEMBL27597505 0.81 DAO (0.48) CES2CES1DAONPC1RAB9A
SCHEMBL28242291 0.79 CES2 (0.43) CES2CES1DAONPC1RAB9A
SCHEMBL5329087 0.79 NPC1 (0.48) CES2CES1DAONPC1RAB9A
SCHEMBL12683491 0.78 CES2 (0.62) CES2CES1DAONPC1RAB9A
SCHEMBL11198165 0.77 CES2 (0.50) CES2CES1DAONPC1RAB9A
SCHEMBL11198155 0.77 CES2 (0.50) CES2CES1DAONPC1RAB9A
SCHEMBL17208838 0.75 L3MBTL1 (0.46) CES2CES1NPC1RAB9AMEN1
SCHEMBL22733861 0.75 ALDH1A1 (0.40) CES2CES1DAONPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1096282-A None JP disclosed
EP-0325742-B1 Phthalocyanine compound and optical recording material using it MITSUBISHI CHEM IND (JP) 1994-03-30 EP disclosed
US-4882428-A PHOTOCHROMIC MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-11-21 US disclosed
EP-0325742-A2 Phthalocyanine compound and optical recording material using it MITSUBISHI KASEI CORPORATION (JP) 1989-08-02 EP disclosed
US-4837063-A CYCLIZABLE BY IRRADIATION WITH LIGHT MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1989-06-06 US disclosed
JP-H0196282-A PHTHALOCYANINE DERIVATIVE IRIE MASAHIRO 1989-04-14 JP disclosed