Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 3/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9396525 | 0.83 | RNASE1 (0.50) | RNASE1POLBBCHE | |
| SCHEMBL23650009 | 0.77 | RNASE1 (0.41) | RNASE1POLBBCHE | |
| SCHEMBL23650012 | 0.77 | RNASE1 (0.41) | RNASE1POLBBCHE | |
| SCHEMBL7993075 | 0.76 | RNASE1 (0.62) | RNASE1 | |
| SCHEMBL7975895 | 0.74 | RNASE1 (0.50) | RNASE1POLBBCHE | |
| SCHEMBL6358753 | 0.73 | TK1 (0.36) | RNASE1 | |
| SCHEMBL6363668 | 0.72 | RNASE1 (0.45) | RNASE1POLB | |
| SCHEMBL8192443 | 0.71 | RNASE1 (0.32) | RNASE1 | |
| SCHEMBL8184687 | 0.71 | RNASE1 (0.33) | RNASE1 | |
| SCHEMBL7788368 | 0.71 | PDE4D (0.45) | RNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022886-A1 | HETEROATOMIC OLIGONUCLEOSIDE LINKAGES | ISIS PHARMACEUTICALS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |