Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 3/20 | 0.39 |
| ▸ | TK2 | O00142 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6363668 | 0.89 | RNASE1 (0.45) | RNASE1POLBTK1TK2PDE4D | |
| SCHEMBL7788368 | 0.86 | PDE4D (0.45) | RNASE1TK1TK2PDE4D | |
| SCHEMBL9702755 | 0.82 | RNASE1 (0.48) | RNASE1TK1TK2PDE4D | |
| SCHEMBL9396525 | 0.81 | RNASE1 (0.50) | RNASE1POLBTK1BCHE | |
| SCHEMBL6358753 | 0.80 | TK1 (0.36) | RNASE1TK1TK2PDE4D | |
| SCHEMBL5977733 | 0.77 | SLC29A1 (0.44) | — | |
| SCHEMBL4660487 | 0.77 | SLC29A1 (0.44) | — | |
| SCHEMBL6363661 | 0.75 | ALDH1A1 (0.34) | RNASE1TK1TK2 | |
| SCHEMBL6362720 | 0.74 | TOP2A (0.34) | RNASE1TK1TK2 | |
| SCHEMBL9396372 | 0.74 | RNASE1 (0.42) | RNASE1POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277982-B1 | REACTING CARBOHYDRATE, OLIGONUCLEOTIDE, NUCLEOTIDE OR NUCLEOSIDE WITH CYCLIC SULFATE; PRODUCTION OF OLIGONUCLEOTIDES WITH IMPROVED HYBRIDIZATION AFFINITY AND NUCLEASE RESISTANCE | ISIS PHARMACEUTICALS, INC. | 2001-08-21 | — | — | US | disclosed |