Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 16/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | WNT1 | P04628 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049722 | 0.84 | ABCC9 (0.40) | ABCC9ABCB1 | |
| SCHEMBL9054344 | 0.84 | HSD11B1 (0.40) | ABCC9LMNA | |
| SCHEMBL9394870 | 0.81 | ABCC9 (0.42) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9092753 | 0.80 | ABCC9 (0.49) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9092749 | 0.80 | ABCC9 (0.49) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9394843 | 0.80 | KCNE1 (0.40) | ABCC9ABCB1 | |
| SCHEMBL9143344 | 0.77 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9143340 | 0.77 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9142294 | 0.77 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 | |
| SCHEMBL9143349 | 0.77 | ABCC9 (0.45) | ABCC9ABCC8KCNJ11KCNJ8CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994020491-A1 | BENZOPYRANES AS POTASSIUM CHANNEL OPENERS | PFIZER LIMITED (GB) | 1994-09-15 | — | — | WO | disclosed |