Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.59 |
| ▸ | PTPRC | P08575 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA9 | Q16790 | 5/20 | 0.48 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL516272 | 0.90 | LMNA (0.58) | S100A4PTPRCLMNAKDM4ECYP1A2 | |
| SCHEMBL30708932 | 0.90 | LMNA (0.58) | S100A4PTPRCLMNAKDM4ECYP1A2 | |
| SCHEMBL9397083 | 0.80 | S100A4 (0.54) | S100A4PTPRCLMNAKDM4EMAPT | |
| SCHEMBL9257330 | 0.79 | S100A4 (0.77) | S100A4PTPRCLMNACYP1A2CYP3A4 | |
| SCHEMBL2347136 | 0.79 | S100A4 (0.84) | S100A4PTPRCLMNACYP1A2CYP3A4 | |
| SCHEMBL1303600 | 0.77 | S100A4 (0.81) | S100A4PTPRCLMNACYP1A2CYP3A4 | |
| SCHEMBL1353874 | 0.76 | LMNA (0.55) | S100A4PTPRCLMNAKDM4ECYP1A2 | |
| SCHEMBL11317413 | 0.75 | S100A4 (0.78) | S100A4PTPRCCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6995634 | 0.75 | ALDH1A1 (0.49) | S100A4PTPRCLMNAKDM4EMAPT | |
| SCHEMBL9642557 | 0.75 | S100A4 (0.66) | S100A4PTPRCLMNAKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027969-A1 | ISOQUINOLINETRIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |