Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398291 | 0.96 | MAPT (0.43) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9344868 | 0.89 | MAPT (0.41) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9398430 | 0.88 | ALDH1A1 (0.62) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9349852 | 0.87 | FTO (0.41) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9397246 | 0.87 | PKM (0.53) | SMN1; SMN2LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL9397177 | 0.85 | ALDH1A1 (0.59) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9198824 | 0.84 | PKM (0.51) | SMN1; SMN2LMNAKDM4EALDH1A1MEN1 | |
| SCHEMBL9345574 | 0.84 | FTO (0.40) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 | |
| SCHEMBL9397241 | 0.82 | FTO (0.43) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL9398483 | 0.82 | KDM4E (0.50) | SMN1; SMN2MAPTLMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |