Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398460 | 0.94 | SIGMAR1 (0.58) | SIGMAR1HRH3SLC6A3TAAR1LMNA | |
| SCHEMBL2091047 | 0.83 | SIGMAR1 (0.72) | SIGMAR1 | |
| SCHEMBL28742033 | 0.82 | SIGMAR1 (0.56) | SIGMAR1HRH3SLC6A3TAAR1HTR1A | |
| SCHEMBL9397258 | 0.81 | SIGMAR1 (0.65) | SIGMAR1HRH3SLC6A3HTR1ASLC6A4 | |
| SCHEMBL662989 | 0.79 | SLC6A3 (0.68) | SIGMAR1SLC6A3HTR1A | |
| SCHEMBL2098145 | 0.78 | SIGMAR1 (0.64) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL1299006 | 0.77 | SIGMAR1 (0.71) | SIGMAR1 | |
| SCHEMBL7989072 | 0.77 | SIGMAR1 (0.84) | SIGMAR1HTR1ASLC6A4 | |
| SCHEMBL9398424 | 0.76 | SIGMAR1 (0.68) | SIGMAR1HRH3SLC6A3SLC6A4 | |
| SCHEMBL13202954 | 0.75 | CARM1 (0.62) | SIGMAR1HRH3TAAR1HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340811-A | Bronchodilator agent | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1994-08-23 | — | — | US | disclosed |
| EP-0471841-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1992-02-26 | — | — | EP | disclosed |