Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.54 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793237 | 0.87 | TP53 (0.71) | LMNAHTTMAPTTP53ALDH1A1 | |
| SCHEMBL6478100 | 0.83 | CTSD (0.62) | HTTMAPTNPSR1TP53PSMB11 | |
| SCHEMBL13753817 | 0.83 | HPGD (0.52) | LMNAHTTTP53ALDH1A1GAA | |
| SCHEMBL25703660 | 0.83 | LMNA (0.68) | LMNAHTTTP53PPARDPPARA | |
| SCHEMBL13753903 | 0.83 | LMNA (1.00) | LMNAHTTMAPTNPSR1DRD2 | |
| SCHEMBL8385196 | 0.82 | TP53 (0.64) | LMNAHTTMAPTNPSR1TP53 | |
| SCHEMBL13293960 | 0.81 | TAS1R3 (0.63) | LMNAHTTMAPTTP53ALDH1A1 | |
| SCHEMBL9983090 | 0.79 | ABCG2 (0.73) | MAPTABCG2 | |
| SCHEMBL9983089 | 0.79 | ABCG2 (0.73) | MAPTABCG2 | |
| SCHEMBL5743965 | 0.78 | HTT (0.62) | LMNAHTTMAPTNPSR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994027969-A1 | ISOQUINOLINETRIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 1994-12-08 | — | — | WO | disclosed |