Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 15/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9398468 | 0.85 | IGFBP5 (0.43) | APP | |
| SCHEMBL9398470 | 0.81 | GRM2 (0.50) | NQO2GRM2LCKLMNA | |
| SCHEMBL14514060 | 0.81 | GRM2 (0.53) | NQO2GRM2LMNA | |
| SCHEMBL247555 | 0.78 | GRM2 (0.59) | GRM2 | |
| Hydrochloric Acid SCHEMBL17769122 | 0.77 | GRM2 (0.57) | GRM2 | |
| SCHEMBL4471851 | 0.73 | IGFBP5 (0.41) | — | |
| SCHEMBL5397578 | 0.73 | POLB (0.41) | LMNAAPP | |
| SCHEMBL27968353 | 0.73 | APP (0.36) | APP | |
| SCHEMBL31603641 | 0.72 | TGFBR1 (0.43) | NQO2LCKLMNA | |
| SCHEMBL14514062 | 0.71 | GRM2 (0.53) | GRM2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344922-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS | 1994-09-06 | — | — | US | disclosed |
| US-5028707-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1991-07-02 | — | — | US | disclosed |
| WO-1991007390-A1 | 4-HYDROXYQUINALDIC ACID DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-05-30 | — | — | WO | disclosed |