Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.50 |
| ▸ | MPO | P05164 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2909734 | 0.85 | MCL1 (0.44) | RXFP1KDM4EALDH1A1 | |
| SCHEMBL9398497 | 0.81 | NQO2 (0.47) | GRM2NQO2LCKLMNA | |
| SCHEMBL14514060 | 0.81 | GRM2 (0.53) | GRM2MPONQO2LMNA | |
| SCHEMBL2906714 | 0.80 | L3MBTL1 (0.47) | NQO2LCKALDH1A1GAA | |
| SCHEMBL247555 | 0.78 | GRM2 (0.59) | GRM2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17769122 | 0.77 | GRM2 (0.57) | GRM2ALDH1A1 | |
| SCHEMBL24151479 | 0.76 | BACE1 (0.53) | GRM2RXFP1LMNADGAT1ALDH1A1 | |
| SCHEMBL24777192 | 0.75 | MPO (0.41) | MPO | |
| SCHEMBL9039085 | 0.73 | ALDH1A1 (0.48) | RXFP1KDM4EALDH1A1GAA | |
| SCHEMBL16832575 | 0.73 | RXFP1 (0.56) | GRM2RXFP1KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5344922-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS | 1994-09-06 | — | — | US | disclosed |
| US-5028707-A | 4-hydroxyquinaldic acid derivatives | BOARD OF REGENTS, UNIVERSITY OF TEXAS (US) | 1991-07-02 | — | — | US | disclosed |
| WO-1991007390-A1 | 4-HYDROXYQUINALDIC ACID DERIVATIVES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 1991-05-30 | — | — | WO | disclosed |