Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 2/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9020556 | 0.96 | CCR5 (0.43) | ALDH1A1MAPTLMNACCR5GPR119 | |
| SCHEMBL9399315 | 0.90 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNACCR5GPR119 | |
| SCHEMBL9020561 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNACCR5GPR119 | |
| SCHEMBL9399205 | 0.86 | CCR5 (0.45) | ALDH1A1MAPTLMNACCR5GPR119 | |
| SCHEMBL16992369 | 0.85 | JAK2 (0.47) | GPR119JAK2JAK1PRMT5NPC1 | |
| SCHEMBL9020154 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTCCR5HPGDNPC1 | |
| SCHEMBL7804752 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTLMNACCR5GPR119 | |
| SCHEMBL9021016 | 0.82 | CCR5 (0.46) | ALDH1A1MAPTLMNACCR5GPR119 | |
| SCHEMBL9020242 | 0.82 | ALDH1A1 (0.43) | ALDH1A1MAPTCCR5HPGDNPC1 | |
| SCHEMBL9020179 | 0.82 | ALDH1A1 (0.41) | ALDH1A1MAPTCCR5HPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5374720-A | A thienamycins bactericides has nontoxic, side effect reduction against the kidney and central nervous system | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |